Lets call them O and B.Ģ) DNA replicates during mitosis so you have two sister chromatids held together by cohesion (O_O and B_B). I suspect that early in development there was a mitotic recombination event (which can happen rarely in response to DNA damage that is repaired through the homologous recombination pathway.) This can create clones of homozygous tissue as follows:ġ) there are two homologous chromosomes, one with the orange fur allele and one with the black fur allele. While the back leg looks like a tortie, the front has much larger solid patches of fur. Because X inactivation results in small clones of cells where one chromosome or the other is inactivated at random, you get patches of skin where only one or the other allele is expressed. Torties arise in a female cat where the two X chromosomes carry different coat alleles (in this case, orange and black). I doubt the cat is a gynandromorph, because the patches at the front are so big (as compared to the more tortoiseshell patterning towards the anterior end). A Google Image search shows out quite a lot of cat canvases! I did not know of him and I just found this image, the mom seems quite anthropomorphised, but here it is”: As Roger noted, “Maybe I missed it if you posted anything from that artist. Reader Roger Latour, however, sent me an email noting that I had missed a good cat artist, Charles van den Eycken (1859-1923), a Belgian painter. I’ve long complained that many artists, even in fairly modern times, seem to have trouble painting cats, especially when they try to be realistic. Inquiring minds want to know! An article in the New Republic suggests, not very clearly, that this involves coordinated inactivation of the X chromosome, the first hypothesis. That’s much rarer, but DNA testing could resolve this, and it wouldn’t cost that much. That chimera can develop into a normal cat that has different genetic constitutions on the two sides-as different as siblings. Or it could be a true chimera, in which two embryos fuse into a single embryo early in development. It could either be differential turning on of X-chromosome linked coat-color (and eye color) genes on one side of the body (this is what causes “split calicos”). Meet the lovely Quimera, who has her own Instagram page.Īs a geneticist, I should know the cause of this, but I’m not sure. Venus is famous for being a “split face” chimera cat with different-colored eyes, but here’s a new and similar cat described by Bored Panda.
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